Everything you wanted to know about cobalamin

I will try to introduce you to one of the vitamins that participate in most processes in the human body. It is vitamin B12, which is mostly found in the human liver (50-90%). Together with folic acid, it belongs to the anti-anemic vitamins. Vitamin B12 works on the growth, formation, and maturation of erythrocytes. Serves as a coenzyme acceptor of hydrogen acts on the proper metabolism of proteins and amino acids. Vitamin B12 plays an important role in converting fats, carbohydrates, and proteins into energy. Vitamin B12 is crucial for the production of genetic material RNA and DNA, and for the production of myelin, which is a protective sheath around nerves.

Symptoms of vitamin B12 deficiency in neurology and psychiatry

It is really amazing that one vitamin acts on the processes in the human body. Neurological symptoms of vitamin B12 deficiency are weakness in the legs, arms, and torso, problems with balance and movement. There are also visual disturbances, loss of taste and smell, stiffness, tingling, muscle spasms, slow reflexes. In addition, there is an inability to control urination or stool, impotence, and depression. Psychiatric symptoms include lethargy, irritability, paranoia, mania, hallucinations, violent behavior, psychosis, personality change, postpartum depression, and psychosis.

Hematological and other symptoms

There are numerous hematological symptoms of vitamin B12 deficiency, anemia, leukopenia, thrombocytopenia, very low reticulocyte count, hypersegmented neutrophils, anisocytosis (erythrocyte size disorder), and pancytopenia (decreased values of all three bloodlines in the peripheral blood).  Other symptoms of vitamin B 12 deficiency include fatigue, general weakness, lack of energy, pallor, weight loss, dizziness, orthostatic hypotension, fainting, falls, tinnitus, shortness of breath on physical exertion, tachycardia, hepatomegaly, splenomegaly, loss of appetite, and loss of appetite. inflammation of the tongue, constipation, diarrhea, and premature gray hair.

Symptoms of vitamin B12 deficiency in children and infants

Vitamin B12 deficiency in children and infants occurs as developmental delay, apathy, irritability, hypotonia, weakness, tremors, convulsions, uncontrolled movements, slow growth, slow head growth, poor motor skills, speech problems, lower IQ, mental retardation, and anemia.

Vitamin B12 occurs in three basic chemical forms. Cyanocobalamin is obtained synthetically and is most common in supplements. Scientists point out that it is the least effective because the organism must convert it into methylcobalamin (physiologically active form). Another form of vitamin B12 is hydroxocobalamin found in meat, liver, fish, seafood, eggs, milk, and dairy products.  The third and only physiologically active form is methylcobalamin. It is the only form that can cross the cerebral blood barrier. It is found in blood plasma, cerebrospinal fluid, and the fluid part of the cytoplasm.  Scientists recommend that it be the first choice in an attempt to improve the health of the nervous system. People who have difficulty absorbing vitamin B12 should ingest higher amounts than recommended for the body to utilize the required amount.  Scientists recommend that it be the first choice in an attempt to improve the health of the nervous system. People who have difficulty absorbing vitamin B12 should ingest higher amounts than recommended for the body to utilize the required amount.